Transferability of Economic Evaluations Across Jurisdictions
A structured approach to determine whether economic evaluations from one healthcare setting can be used in another, and how to adapt them appropriately.
At a glance
Use when
Applying economic evidence from one country to another, especially in early stages of HTA or when local data are scarce
Avoid when
Local data and context are substantially different and poorly understood, or when high decision impact demands primary economic evaluation
Inputs
Economic evaluation data from a source jurisdiction, contextual data from the target jurisdiction (e.g., costs, resource use, epidemiology)
Outputs
Assessment of transferability, recommendations for adaptation or need for de novo analysis
How it works
Developed by the ISPOR Good Research Practices Task Force, this framework provides guidance on assessing the transferability of economic evaluations across jurisdictions by evaluating differences in healthcare systems, costs, epidemiology, and practice patterns. It supports decisions on whether to adapt existing studies or conduct new analyses.
- HTA domains
- Costs & Economic Evaluation, Organisational aspects, Aspects Beyond HTA
- Assumptions
- Key parameters influencing cost-effectiveness vary systematically across jurisdictions; adaptation can preserve validity
- Strengths
- Systematic consideration of contextual differences; reduces duplication of effort; promotes efficient use of evidence
- Limitations
- May not capture all local nuances; requires expert judgment; limited guidance on quantifying adjustments
Questions this answers
References & sources
Related methods
Similar by meaning
Beta record. Based on the original catalogue summary; primary-source enrichment pending.