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Toolkit for assessing the transferability of evidence across contexts

Toolpeer-reviewed✓ Source-grounded

This toolkit helps decision-makers evaluate how well health technology assessment evidence from one setting can be applied to another, especially when resources or systems differ. It guides users in assessing whether a health technology will work in their local context by looking at organizational, economic, and social factors.

At a glance

Use when

Adapting HTA evidence from high-income to low- or middle-income countries; when local HTA capacity is limited; when implementing technologies in different organizational or cultural contexts

Avoid when

Local context is vastly different with no reliable adaptation pathway; when primary data collection is feasible and preferred; when the original HTA is of poor quality or outdated

Inputs

Contextual data from source and target settings (e.g., organizational structure, resource availability, epidemiological profiles, health system characteristics)

Outputs

Assessment of transferability across HTA domains, identification of adaptation needs, and recommendations for local applicability

How it works

The toolkit supports the systematic assessment of contextual factors influencing the transferability of health technology assessments (HTAs), particularly across diverse settings including low- and middle-income countries. It follows the standard HTA process but adds structured steps to evaluate applicability, quality, and adaptability of evidence across domains. It enables adaptation of HTA parameters to local contexts and supports evidence-informed decision-making where local HTA capacity is limited.

Project
IMPACT HTA
Funding
Horizon 2020
Project status
Completed 2021
HTA domains
Organisational aspects
Technology
Non-specific
Assumptions
Evidence from one context can be meaningfully adapted to another; key contextual differences can be identified and addressed; local decision-makers have access to some HTA evidence
Strengths
Reduces duplication of HTA efforts; supports use of existing evidence in resource-limited settings; covers multiple HTA domains; promotes systematic consideration of context
Limitations
May require expert judgment to interpret contextual differences; limited empirical validation in low-resource settings; most tools focus on economic evaluations, with fewer addressing broader HTA aspects
Also known as
Transferability Assessment Toolkit

Questions this answers

References & sources

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Beta record. Generated from the primary source via AI extraction and independent audit, pending final human review.