Norwegian and Swedish value sets for the EORTC QLU-C10D (cancer utility)
These value sets provide population-specific utility weights for the EORTC QLU-C10D, a cancer-specific quality-of-life instrument, based on preferences from representative samples of people in Norway and Sweden. They help convert patient-reported health states into quality-adjusted life years (QALYs) for use in economic evaluations of cancer treatments.
At a glance
Use when
Conducting cost-utility analyses in cancer care in Norway or Sweden; mapping EORTC QLU-C10D outcomes to utilities; informing HTA submissions requiring country-specific utility weights
Avoid when
Working in non-Scandinavian countries; when disease-specific utility instruments with local weights are available; if real-world patient utility data from clinical trials are accessible
Inputs
Health state descriptions from the EORTC QLU-C10D, including domain scores and duration
Outputs
Utility weights (preference values) for cancer-specific health states, enabling QALY calculation
How it works
Utility weights for the EORTC QLU-C10D were derived using a discrete choice experiment with 960 choice sets completed by 1019 Norwegian and 1048 Swedish participants representative of the general population. Generalized estimating equation models were used to estimate utility decrements for each domain level. Non-monotonic levels were merged to ensure consistent valuation. The resulting value sets enable mapping of EORTC QLU-C10D health states to utility scores for cost-utility analysis in Norway and Sweden.
- HTA domains
- Clinical Effectiveness, Costs & Economic Evaluation, Patient and Social Aspects
- Categories
- HRQoL
- Assumptions
- Population preferences are stable and generalizable; health state valuations are consistent across durations; utility decrements are additive within the model
- Strengths
- Based on representative population samples; uses robust discrete choice experiment methodology; accounts for non-monotonic preferences; provides country-specific weights for more accurate HTA
- Limitations
- Limited to Norwegian and Swedish contexts; may not capture all nuances of cancer-related quality of life; derived from hypothetical health states rather than real-world patient experience
- Also known as
- EORTC QLU-C10D Norwegian value set, EORTC QLU-C10D Swedish value set
Questions this answers
- › How can EORTC QLU-C10D health states be converted into utility values for cost-utility analysis?
- › What are the relative impacts of different cancer-related symptoms and functioning domains on quality of life in Norway and Sweden?
- › How do Norwegian and Swedish population preferences differ in valuing cancer health states?
- › How can health state utilities be estimated for cancer patients in population-based studies?
- › What is the disutility associated with severe pain or nausea in cancer patients according to Norwegian and Swedish preferences?
- › How can country-specific utility weights improve the accuracy of HTA submissions in Norway and Sweden?
References & sources
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