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Swedish experience-based EQ-5D-3L value sets (Burström)

Value setpeer-reviewed✓ Source-grounded

This value set provides Swedish population-based values for different health states measured by the EQ-5D-3L instrument, based on real-life health experiences of around 45,000 people. It helps estimate quality-adjusted life years (QALYs) using values that reflect how Swedes actually experience their health, rather than hypothetical scenarios.

At a glance

Use when

Conducting health economic evaluations in Sweden, especially for reimbursement submissions requiring experience-based utility values; when mental health impact needs accurate representation; when using EQ-5D-3L data from Swedish populations

Avoid when

When a hypothetical valuation perspective is required; when applying to non-Swedish populations; when using EQ-5D-5L or other variants without cross-walking

Inputs

EQ-5D-3L health state profiles from individuals or populations, optionally including demographic covariates (age, sex, education, socioeconomic group)

Outputs

Utility values (on a 0–1 scale) for EQ-5D-3L health states based on Swedish population experience, including TTO-based and VAS-based value sets

How it works

The value set was derived from a large general population survey (n ≈ 45,000) linking EQ-5D-3L responses to experience-based time trade-off (TTO) and visual analogue scale (VAS) valuations. Multivariate regression models were used to estimate the impact of each EQ-5D dimension and severity level on TTO and VAS scores. The value set accounts for age, sex, education, and socioeconomic group, though these had modest effects. Anxiety/depression had the largest negative impact on health valuations. The set supports QALY calculation in economic evaluations consistent with Swedish reimbursement guidelines.

HTA domains
Clinical Effectiveness, Patient and Social Aspects
Categories
HRQoL
Assumptions
Health state valuations are consistent across subgroups; the EQ-5D-3L adequately captures relevant aspects of health; experience-based values reflect societal preferences sufficiently for economic evaluation purposes
Strengths
Based on a very large, nationally representative sample (n ≈ 45,000),Uses experience-based valuation (TTO and VAS), aligning with patient-centered and real-world health assessment,Supports national HTA and reimbursement guidelines in Sweden,Highlights the significant impact of mental health on quality of life
Limitations
Does not include valuation of the worst health state via TTO (due to floor effects),Limited impact of usual activities dimension in modeling,Modest improvement in explanatory power when including sociodemographic variables,May not be generalizable to other countries or cultures
Also known as
Burström EQ-5D-3L value set, Swedish EQ-5D-3L experience-based values, Swedish TTO-based EQ-5D value set

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