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Swedish EQ-5D-5L experience-based value sets (Burström TTO & VAS)

Value setpeer-reviewed✓ Source-grounded

These are Swedish value sets for the EQ-5D-5L health questionnaire, based on real people's evaluations of their own health using two methods: time trade-off (TTO) and visual analogue scale (VAS). They help convert health descriptions into single numbers that reflect how good or bad a health state is, based on actual patient experiences. This makes them useful for comparing treatments and making fair healthcare decisions.

At a glance

Use when

Conducting health technology assessments in Sweden that require utility weights based on experienced health states; preference for population-level, experience-based valuation over hypothetical scenario valuation; need for both TTO and VAS-based scoring for sensitivity analysis.

Avoid when

When hypothetical valuation (e.g., general population time trade-off) is preferred; when working in non-Swedish contexts without cross-cultural validation; when detailed valuation of rare or unobserved health states is required without imputation.

Inputs

EQ-5D-5L health state profiles (five dimensions at five severity levels) from individuals currently experiencing those states, along with their TTO and VAS self-valuations.

Outputs

Single-index utility values for all 3125 EQ-5D-5L health states, based on Swedish population experience using TTO and VAS methods.

How it works

Experience-based value sets for the EQ-5D-5L were developed using data from a large population-based postal survey (n=25,867) in Sweden. TTO (n=13,381) and VAS (n=23,899) valuations of respondents' current health states were modeled using ordinary least-squares regression. The models included 20 dummy variables for severity increments across five dimensions and interaction terms for severity thresholds (N2–N5). In the TTO model, levels 4 and 5 were combined for mobility, self-care, and usual activities; N5 was included to distinguish the worst states. In the VAS model, only mobility levels 4 and 5 were combined, and N2–N4 interactions were significant. These are the first TTO-based EQ-5D-5L value sets derived from experienced health states.

HTA domains
Clinical Effectiveness, Patient and Social Aspects
Categories
HRQoLPROMs
Assumptions
Respondents can accurately self-value their current health using TTO and VAS; statistical models adequately capture the structure of health state preferences; combining certain severity levels does not bias utility estimates.
Strengths
First experience-based EQ-5D-5L TTO value set; large, representative population sample; uses actual experienced health states rather than hypothetical ones; includes both TTO and VAS valuation methods; models interaction effects for severe health states.
Limitations
Only 28.7% of possible health states were observed; some levels had to be combined due to sparse data; self-administered survey may introduce response bias; generalizability to other populations may be limited.
Also known as
Burström EQ-5D-5L Swedish value sets, Swedish experience-based EQ-5D-5L TTO/VAS values, EQ-5D-5L SE TTO & VAS value sets

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Beta record. Generated from the primary source via AI extraction and independent audit, pending final human review.