EQ-5D-Y-3L value sets

This is a set of values that helps measure how different health conditions affect the quality of life of children and adolescents, specifically from the perspective of a 10-year-old child. It was developed for use in Slovenia but is the first such set available globally for the EQ-5D-Y-3L questionnaire.

How it works

The EQ-5D-Y-3L value set for Slovenia was derived using a discrete-choice experiment (DCE) with 1074 adults who evaluated health states by assuming the perspective of a 10-year-old child. The value of the worst health state (33333) was anchored using 200 composite time trade-off (cTTO) interviews. A mixed logit model was used to estimate the coefficients, all of which were statistically significant and showed expected negative signs. Pain/discomfort had the largest impact on health state valuation, followed by anxiety/depression, usual activities, mobility, and self-care.

Project

IMPACT HTA

Funding

Horizon 2020

Project status

Completed 2021

HTA domains

Costs & Economic Evaluation

Categories

HRQoL

Technology

Non-specific

Assumptions

Adults can accurately proxy the health state preferences of a 10-year-old child; the latent scale in DCE data is corrected using cTTO anchoring; health state values are transferable across populations with similar cultural context

Strengths

First EQ-5D-Y-3L value set published globally; follows international valuation protocol; large, representative sample; uses both DCE and cTTO methods; robust statistical modeling with mixed logit approach

Limitations

Relies on adult proxy valuation rather than child self-report; online survey may introduce selection bias; cultural specificity limits generalizability to other countries

Geographic & clinical scope

Germany; Slovenia; Spain

Also known as

EQ-5D-Y value set for Slovenia, EQ-5D-Y-3L Slovenia value set

Beta record. Generated from the primary source via AI extraction and independent audit, pending final human review.