EORTC QLU-C10D
The EORTC QLU-C10D is a tool used to measure health-related quality of life in cancer patients. It converts patient responses into a single score that reflects overall health, which can be used to calculate quality-adjusted life years (QALYs) in cancer studies.
At a glance
Use when
Conducting economic evaluations in oncology and needing to derive utility values from EORTC QLQ-C30 data
Avoid when
Working outside oncology or when using non-EORTC QLQ-C30 data sources
Inputs
Responses from the EORTC QLQ-C30 questionnaire
Outputs
10-dimensional health state classification and utility score for QALY calculation
How it works
The EORTC QLU-C10D is a cancer-specific multi-attribute utility instrument with a 10-dimension health-state classification system derived from the EORTC QLQ-C30. It enables the derivation of utility values for use in economic evaluations, particularly in oncology health technology assessment (HTA), by mapping QLQ-C30 data to a preference-based index for QALY calculation.
- HTA domains
- Clinical Effectiveness, Patient and Social Aspects
- Assumptions
- The mapping from QLQ-C30 to utility values is valid and generalizable across cancer populations; dimension weights reflect societal preferences
- Strengths
- Cancer-specific design ensures relevance; derived from widely used QLQ-C30; enables QALY estimation in oncology where generic instruments may lack sensitivity
- Limitations
- Limited to cancer populations; dependent on the quality and completeness of QLQ-C30 input data; may not capture all aspects valued in economic evaluations
- Also known as
- EORTC QLU-C10D, QLU-C10D
Questions this answers
- › What is the patient's health-related quality of life across key cancer-specific domains?
- › How can QLQ-C30 data be transformed into utility values for economic evaluation?
- › What is the health state utility value for a given cancer patient profile?
- › How do different cancer treatments compare in terms of quality-adjusted survival?
- › Can this instrument support QALY estimation in oncology HTA submissions?
- › Is the impact of cancer and its treatment captured in a way that aligns with preference-based measures?
References & sources
Similar by meaning
- Validation of the cancer-specific utility measure EORTC QLU-C10D using evidence from four lung cancer trials covering six country value sets
- EORTC QLU-C10D Australian utility weights
- German value sets for the EORTC QLU-C10D, a cancer-specific utility instrument based on the EORTC QLQ-C30
- Danish value sets for the EORTC QLU-C10D (cancer utility)
- Japanese value set for the EORTC QLU-C10D: A multi-attribute utility instrument based on the EORTC QLQ-C30 cancer-specific quality-of-life questionnaire
Beta record. Based on the original catalogue summary; primary-source enrichment pending.