Lung cancer rehabilitation clinical core outcome set
This core outcome set defines six key outcomes that should be measured when evaluating lung cancer rehabilitation programs in clinical practice. It helps ensure consistent and patient-centered assessment across different settings.
At a glance
Use when
Designing or evaluating lung cancer rehabilitation programs in clinical practice where standardized, patient-relevant outcomes are needed.
Avoid when
Conducting economic or organizational evaluations that require cost or system-level metrics beyond clinical and patient-reported outcomes.
Inputs
Stakeholder ratings on outcome importance and instrument suitability from Delphi surveys and consensus meetings.
Outputs
A standardized set of six core outcomes and two agreed-upon measurement instruments for physical function and HRQoL.
How it works
Developed through an international modified Delphi study with patients, carers, healthcare professionals, and researchers, this clinical core outcome set includes six outcomes: breathlessness, activities of daily living, physical function, health-related quality of life (HRQoL), emotional and mental wellbeing, and pain. Consensus was reached on measurement instruments for physical function (6-min walk test) and HRQoL (EORTC QLQ-C30), but not for the other outcomes. Two Delphi rounds and online consensus meetings were conducted.
- Project
- H2O
- Funding
- IMI
- Project status
- Ongoing
- HTA domains
- Clinical Effectiveness, Patient and Social Aspects
- Assumptions
- Outcomes considered critical by a diverse, international panel reflect minimum standards for clinical evaluation in lung cancer rehabilitation.
- Strengths
- Incorporates multi-stakeholder perspectives including patients and carers; follows COS development guidelines; high retention rate in Delphi rounds.
- Limitations
- Lack of consensus on measurement instruments for four of the six core outcomes; limited patient participation in Phase Two.
- Also known as
- Lung cancer rehabilitation COS, H2O Lung Cancer Rehabilitation Core Outcome Set
Questions this answers
- › Which outcomes are essential to measure in lung cancer rehabilitation?
- › How can clinical evaluation of lung cancer rehabilitation be standardized?
- › What patient-centered outcomes are prioritized by stakeholders in lung cancer rehabilitation?
- › Which measurement instruments are recommended for physical function in lung cancer rehabilitation?
- › Which tool is recommended for assessing health-related quality of life in this context?
- › What outcomes lack consensus on measurement instruments in current practice?
References & sources
Related methods
Similar by meaning
- Core outcome set for multiple myeloma
- Core outcome set for metastatic breast cancer (MBC)
- Core outcome set for inflammatory bowel disease (IBD)
- Core outcome set for diabetes
- Validation of the cancer-specific utility measure EORTC QLU-C10D using evidence from four lung cancer trials covering six country value sets
Beta record. Generated from the primary source via AI extraction and independent audit, pending final human review.

