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Lung cancer rehabilitation clinical core outcome set

Value setpeer-reviewed✓ Source-grounded

This core outcome set defines six key outcomes that should be measured when evaluating lung cancer rehabilitation programs in clinical practice. It helps ensure consistent and patient-centered assessment across different settings.

At a glance

Use when

Designing or evaluating lung cancer rehabilitation programs in clinical practice where standardized, patient-relevant outcomes are needed.

Avoid when

Conducting economic or organizational evaluations that require cost or system-level metrics beyond clinical and patient-reported outcomes.

Inputs

Stakeholder ratings on outcome importance and instrument suitability from Delphi surveys and consensus meetings.

Outputs

A standardized set of six core outcomes and two agreed-upon measurement instruments for physical function and HRQoL.

How it works

Developed through an international modified Delphi study with patients, carers, healthcare professionals, and researchers, this clinical core outcome set includes six outcomes: breathlessness, activities of daily living, physical function, health-related quality of life (HRQoL), emotional and mental wellbeing, and pain. Consensus was reached on measurement instruments for physical function (6-min walk test) and HRQoL (EORTC QLQ-C30), but not for the other outcomes. Two Delphi rounds and online consensus meetings were conducted.

Project
H2O
Funding
IMI
Project status
Ongoing
HTA domains
Clinical Effectiveness, Patient and Social Aspects
Assumptions
Outcomes considered critical by a diverse, international panel reflect minimum standards for clinical evaluation in lung cancer rehabilitation.
Strengths
Incorporates multi-stakeholder perspectives including patients and carers; follows COS development guidelines; high retention rate in Delphi rounds.
Limitations
Lack of consensus on measurement instruments for four of the six core outcomes; limited patient participation in Phase Two.
Also known as
Lung cancer rehabilitation COS, H2O Lung Cancer Rehabilitation Core Outcome Set

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