Approaches to Aggregation and Decision Making—A Health Economics Approach
This framework helps decision makers combine different types of evidence, especially health outcomes and costs, to assess the value of health interventions using economic principles. It supports structured thinking about what makes a treatment valuable.
At a glance
Use when
When developing or evaluating value assessment frameworks, conducting health technology assessments, or designing reimbursement policies
Avoid when
When a purely clinical or non-economic perspective is sufficient, or when economic data are unavailable and cannot be reasonably estimated
Inputs
Clinical outcomes, cost data, patient-reported outcomes, preference weights
Outputs
Aggregated value measures, decision recommendations based on economic efficiency and equity
How it works
A conceptual and methodological framework developed by the ISPOR Special Task Force for aggregating outcomes and informing decision making in health technology assessment and value-based pricing. It applies health economics principles to integrate clinical, economic, and patient-centered outcomes into coherent value assessments.
- HTA domains
- Clinical Effectiveness, Costs & Economic Evaluation
- Categories
- AppraisalCost-effectiveness Modelling
- Assumptions
- Outcomes can be meaningfully measured and weighted; decision makers seek value for money; equity and patient preferences are relevant to value
- Strengths
- Provides a structured, transparent approach to value assessment; integrates economic efficiency with equity and patient-centered considerations; developed by a multidisciplinary expert group
- Limitations
- May require subjective judgments in weighting outcomes; implementation depends on data availability and stakeholder consensus; not a quantitative model itself but a guiding framework
Questions this answers
References & sources
Related methods
Similar by meaning
- ICER Value Framework 2020 Update - Aggregation of Benefits and Contextual Considerations
- WHO-CHOICE Generalized Cost-Effectiveness Analysis (updated methodology)
- Generalized Risk-Adjusted Cost-Effectiveness (GRACE)
- EVIDEM Framework
- A Framework for Developing the Structure of Public Health Economic Models
Beta record. Based on the original catalogue summary; primary-source enrichment pending.